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Ayşan Gruda, 1977 yılında 16 senelik tiyatro hayatından sonra televizyonda bir eğlence programı içinde yayınlanan skeçte canlandırdığı "Domates Güzeli Nahide Şerbet" karakteriyle adını geniş kitlelere duyurdu.
Yeşilçam'ın 'domates güzeli' olarak hafızalara kazınan oyuncu, sinemada "Tosun Paşa", "Süt Kardeşler", "Şabanoğlu Şaban", "Hababam Sınıfı", "Neşeli Günler" gibi birçok klasikleşmiş Türk sineması örneklerinde oynadı.
Oyunculuk performansıyla 7'den 70'e geniş bir hayran kitlesine ulaşan Gurda, başrolünü Kemal Sunal ile üstlendiği filmlerinden biri olan Avanak Apti'nin televizyon ekranlarında yayınlanması üzerine gündem oldu.
Filmde Nevin karakterini canlandıran merhum sanatçı Ayşen Gruda'nın hayatı ise merak edilip araştırılmaya başlandı.
23 Ocak 2019 tarihinde 74 yaşında aramızdan ayrılan Gruda'nın özellikle memleketi merak edilerek "Ayşen Gruda aslen nereli?" sorusunun yanıtı aratıldı.